STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ING5Inhibitor of growth family member 5. (254 aa)    
Predicted Functional Partners:
MEAF6
MYST/Esa1 associated factor 6.
   
 0.974
KAT7
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
 0.966
KAT6A
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
 0.959
BRPF3
Bromodomain and PHD finger containing 3.
    
 0.917
BRD1
Bromodomain containing 1.
    
 0.909
BRPF1
Bromodomain and PHD finger containing 1.
    
 0.899
JADE1
Jade family PHD finger 1.
    
 0.889
JADE2
Jade family PHD finger 2.
    
 0.887
KAT6B
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
 0.870
TP53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.858
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.