Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EEPD1Endonuclease/exonuclease/phosphatase family domain containing 1. (569 aa)    
Predicted Functional Partners:
SUPT16H
SPT16 homolog, facilitates chromatin remodeling subunit.
   
 0.803
IWS1
Interacts with SUPT6H, CTD assembly factor 1.
   
 0.780
SSRP1
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
 0.779
CDC73
Cell division cycle 73.
   
 0.692
POLR2E
RNA polymerase II subunit E.
    
 0.652
POLR2D
RNA polymerase II subunit D.
    
 0.635
POLR2G
RNA polymerase II subunit G.
    
 0.632
RTF1
RTF1 homolog, Paf1/RNA polymerase II complex component.
   
 
 0.585
LOC105503213
Uncharacterized protein.
    
   0.571
ELOF1
Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family.
    
 
 0.567
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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