MAP3K9 protein (Colobus angolensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MAP3K9

Mitogen-activated protein kinase kinase kinase. (997 aa)

Predicted Functional Partners:

MAP2K7

0.739

HTT

0.670

TAB1

0.639

CD247

0.620

MIB2

0.613

TRAF6

0.597

FADD

0.551

TRADD

0.531

ITSN2

0.520

MYD88

0.512

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD247	FADD	ENSCANP00000015522	ENSCANP00000013072	CD247 molecule.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.457
CD247	MAP3K9	ENSCANP00000015522	ENSCANP00000007056	CD247 molecule.	Mitogen-activated protein kinase kinase kinase.	0.620
FADD	CD247	ENSCANP00000013072	ENSCANP00000015522	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	CD247 molecule.	0.457
FADD	ITSN2	ENSCANP00000013072	ENSCANP00000006595	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Intersectin 2.	0.520
FADD	MAP3K9	ENSCANP00000013072	ENSCANP00000007056	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Mitogen-activated protein kinase kinase kinase.	0.551
FADD	MIB2	ENSCANP00000013072	ENSCANP00000006147	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Mindbomb E3 ubiquitin protein ligase 2.	0.612
FADD	MYD88	ENSCANP00000013072	ENSCANP00000030953	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.929
FADD	TAB1	ENSCANP00000013072	ENSCANP00000017221	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	TGF-beta activated kinase 1 (MAP3K7) binding protein 1.	0.633
FADD	TRADD	ENSCANP00000013072	ENSCANP00000020353	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	TNFRSF1A associated via death domain.	0.987
FADD	TRAF6	ENSCANP00000013072	ENSCANP00000017842	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.635
HTT	MAP3K9	ENSCANP00000020299	ENSCANP00000007056	Huntingtin.	Mitogen-activated protein kinase kinase kinase.	0.670
ITSN2	FADD	ENSCANP00000006595	ENSCANP00000013072	Intersectin 2.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.520
ITSN2	MAP3K9	ENSCANP00000006595	ENSCANP00000007056	Intersectin 2.	Mitogen-activated protein kinase kinase kinase.	0.520
MAP2K7	MAP3K9	ENSCANP00000002031	ENSCANP00000007056	Mitogen-activated protein kinase kinase 7.	Mitogen-activated protein kinase kinase kinase.	0.739
MAP2K7	TAB1	ENSCANP00000002031	ENSCANP00000017221	Mitogen-activated protein kinase kinase 7.	TGF-beta activated kinase 1 (MAP3K7) binding protein 1.	0.844
MAP2K7	TRADD	ENSCANP00000002031	ENSCANP00000020353	Mitogen-activated protein kinase kinase 7.	TNFRSF1A associated via death domain.	0.818
MAP2K7	TRAF6	ENSCANP00000002031	ENSCANP00000017842	Mitogen-activated protein kinase kinase 7.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.484
MAP3K9	CD247	ENSCANP00000007056	ENSCANP00000015522	Mitogen-activated protein kinase kinase kinase.	CD247 molecule.	0.620
MAP3K9	FADD	ENSCANP00000007056	ENSCANP00000013072	Mitogen-activated protein kinase kinase kinase.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.551
MAP3K9	HTT	ENSCANP00000007056	ENSCANP00000020299	Mitogen-activated protein kinase kinase kinase.	Huntingtin.	0.670