STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (670 aa)    
Predicted Functional Partners:
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
  
 
0.985
ITSN2
Intersectin 2.
   
 0.952
IGDCC3
Immunoglobulin superfamily DCC subclass member 3.
    
  0.942
FNDC1
Fibronectin type III domain containing 1.
    
  0.942
IGDCC4
Immunoglobulin superfamily DCC subclass member 4.
    
  0.942
NEO1
Neogenin 1.
    
  0.942
DCC
DCC netrin 1 receptor.
    
 0.942
AKT1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 
 0.907
AKT2
AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily.
    
 
 0.907
AKT3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 
 0.907
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.