STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
INSRRTyrosine-protein kinase receptor. (1301 aa)    
Predicted Functional Partners:
IGF1
Insulin like growth factor 1.
    
 0.958
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.958
PTPN1
Tyrosine-protein phosphatase non-receptor type.
    
 0.933
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.920
PIK3R2
Uncharacterized protein.
    
 0.920
PIK3R3
Phosphoinositide-3-kinase regulatory subunit 3.
    
 0.920
IGF1R
Tyrosine-protein kinase receptor.
  
 
0.886
INSR
Tyrosine-protein kinase receptor.
  
 
 
0.876
GRB2
Uncharacterized protein.
   
 0.870
IRS1
Insulin receptor substrate 1.
    
 0.864
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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