STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHG5Pleckstrin homology and RhoGEF domain containing G5. (1071 aa)    
Predicted Functional Partners:
TNF
Tumor necrosis factor; Belongs to the tumor necrosis factor family.
    
 0.864
TRADD
TNFRSF1A associated via death domain.
    
 0.853
RND3
Rho family GTPase 3.
    
 0.840
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.838
ARHGEF11
Rho guanine nucleotide exchange factor 11.
    
0.833
ARHGEF12
Rho guanine nucleotide exchange factor 12.
    
0.833
ARHGEF1
Rho guanine nucleotide exchange factor 1.
    
0.805
LTA
Lymphotoxin alpha; Belongs to the tumor necrosis factor family.
    
 0.796
TNFAIP3
TNF alpha induced protein 3.
    
 0.765
RNF31
Uncharacterized protein.
    
 0.759
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.