STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAPGEF1Rap guanine nucleotide exchange factor 1. (1095 aa)    
Predicted Functional Partners:
CRKL
CRK like proto-oncogene, adaptor protein.
    
 0.992
CRK
CRK proto-oncogene, adaptor protein.
    
 0.987
CBL
Cbl proto-oncogene.
    
 0.943
GRB2
Uncharacterized protein.
   
 0.903
RAP1A
RAP1A, member of RAS oncogene family.
    
 0.902
CBLB
Cbl proto-oncogene B.
    
 0.893
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 0.892
CDH1
Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.
     
 0.836
LOC105501165
Uncharacterized protein.
    
 0.782
RHOQ
Uncharacterized protein.
    
 0.782
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.