TET1 protein (Colobus angolensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TET1

Tet methylcytosine dioxygenase 1. (2131 aa)

Predicted Functional Partners:

PRM2

0.602

GADD45A

0.579

CXXC5

0.571

SIN3A

0.565

DNMT3A

0.551

OGT

0.546

DNMT1

0.539

PRMT5

0.533

TDG

0.531

PRDM14

0.525

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CXXC5	TET1	ENSCANP00000029661	ENSCANP00000008887	CXXC finger protein 5.	Tet methylcytosine dioxygenase 1.	0.571
DNMT1	DNMT3A	ENSCANP00000019277	ENSCANP00000027757	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.955
DNMT1	SIN3A	ENSCANP00000019277	ENSCANP00000021660	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	SIN3 transcription regulator family member A.	0.753
DNMT1	TDG	ENSCANP00000019277	ENSCANP00000027307	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Thymine DNA glycosylase.	0.553
DNMT1	TET1	ENSCANP00000019277	ENSCANP00000008887	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Tet methylcytosine dioxygenase 1.	0.539
DNMT3A	DNMT1	ENSCANP00000027757	ENSCANP00000019277	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.955
DNMT3A	PRDM14	ENSCANP00000027757	ENSCANP00000014909	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	PR/SET domain 14.	0.436
DNMT3A	PRMT5	ENSCANP00000027757	ENSCANP00000013398	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily.	0.659
DNMT3A	TDG	ENSCANP00000027757	ENSCANP00000027307	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Thymine DNA glycosylase.	0.577
DNMT3A	TET1	ENSCANP00000027757	ENSCANP00000008887	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Tet methylcytosine dioxygenase 1.	0.551
GADD45A	TDG	ENSCANP00000036621	ENSCANP00000027307	Growth arrest and DNA damage inducible alpha.	Thymine DNA glycosylase.	0.681
GADD45A	TET1	ENSCANP00000036621	ENSCANP00000008887	Growth arrest and DNA damage inducible alpha.	Tet methylcytosine dioxygenase 1.	0.579
OGT	SIN3A	ENSCANP00000017141	ENSCANP00000021660	O-linked N-acetylglucosamine (GlcNAc) transferase.	SIN3 transcription regulator family member A.	0.485
OGT	TET1	ENSCANP00000017141	ENSCANP00000008887	O-linked N-acetylglucosamine (GlcNAc) transferase.	Tet methylcytosine dioxygenase 1.	0.546
PRDM14	DNMT3A	ENSCANP00000014909	ENSCANP00000027757	PR/SET domain 14.	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.436
PRDM14	TET1	ENSCANP00000014909	ENSCANP00000008887	PR/SET domain 14.	Tet methylcytosine dioxygenase 1.	0.525
PRM2	TET1	ENSCANP00000008132	ENSCANP00000008887	Protamine 2.	Tet methylcytosine dioxygenase 1.	0.602
PRMT5	DNMT3A	ENSCANP00000013398	ENSCANP00000027757	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily.	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.659
PRMT5	TET1	ENSCANP00000013398	ENSCANP00000008887	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily.	Tet methylcytosine dioxygenase 1.	0.533
SIN3A	DNMT1	ENSCANP00000021660	ENSCANP00000019277	SIN3 transcription regulator family member A.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.753