STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHRNGCholinergic receptor nicotinic gamma subunit. (517 aa)    
Predicted Functional Partners:
SLURP1
Secreted LY6/PLAUR domain containing 1.
     
 0.819
SLURP2
Secreted LY6/PLAUR domain containing 2.
     
 0.817
CHRNA1
Cholinergic receptor nicotinic alpha 1 subunit.
  
0.796
EIF4E2
Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family.
      
 0.662
KIF2A
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
      
 0.659
OCRL
OCRL inositol polyphosphate-5-phosphatase.
      
 0.621
MED19
Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.621
CLCN6
Chloride voltage-gated channel 6; Belongs to the chloride channel (TC 2.A.49) family.
      
 0.616
PRPF3
Pre-mRNA processing factor 3.
      
 0.600
CHRNA2
Cholinergic receptor nicotinic alpha 2 subunit.
  
 
0.590
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.