AREL1 protein (Colobus angolensis) - STRING interaction network

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Score

AREL1

Apoptosis resistant E3 ubiquitin protein ligase 1. (823 aa)

Predicted Functional Partners:

TRIP12

0.823

ENSCANP00000004314

0.673

ENSCANP00000034772

0.673

FAU

0.673

UBE2D1

0.604

MTX2

0.589

ATG7

0.533

TRRAP

0.507

ENSCANP00000038732

0.507

DDIT4

0.495

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AREL1	ATG7	ENSCANP00000010475	ENSCANP00000021890	Apoptosis resistant E3 ubiquitin protein ligase 1.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.533
AREL1	DDIT4	ENSCANP00000010475	ENSCANP00000019615	Apoptosis resistant E3 ubiquitin protein ligase 1.	DNA damage inducible transcript 4.	0.495
AREL1	ENSCANP00000004314	ENSCANP00000010475	ENSCANP00000004314	Apoptosis resistant E3 ubiquitin protein ligase 1.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.673
AREL1	ENSCANP00000034772	ENSCANP00000010475	ENSCANP00000034772	Apoptosis resistant E3 ubiquitin protein ligase 1.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.673
AREL1	ENSCANP00000038732	ENSCANP00000010475	ENSCANP00000038732	Apoptosis resistant E3 ubiquitin protein ligase 1.	Uncharacterized protein.	0.507
AREL1	FAU	ENSCANP00000010475	ENSCANP00000036636	Apoptosis resistant E3 ubiquitin protein ligase 1.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.673
AREL1	MTX2	ENSCANP00000010475	ENSCANP00000017821	Apoptosis resistant E3 ubiquitin protein ligase 1.	Metaxin 2.	0.589
AREL1	TRIP12	ENSCANP00000010475	ENSCANP00000002725	Apoptosis resistant E3 ubiquitin protein ligase 1.	Thyroid hormone receptor interactor 12.	0.823
AREL1	TRRAP	ENSCANP00000010475	ENSCANP00000029197	Apoptosis resistant E3 ubiquitin protein ligase 1.	Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family.	0.507
AREL1	UBE2D1	ENSCANP00000010475	ENSCANP00000010288	Apoptosis resistant E3 ubiquitin protein ligase 1.	Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family.	0.604
ATG7	AREL1	ENSCANP00000021890	ENSCANP00000010475	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Apoptosis resistant E3 ubiquitin protein ligase 1.	0.533
ATG7	ENSCANP00000004314	ENSCANP00000021890	ENSCANP00000004314	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.539
ATG7	ENSCANP00000034772	ENSCANP00000021890	ENSCANP00000034772	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.539
ATG7	FAU	ENSCANP00000021890	ENSCANP00000036636	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.539
ATG7	TRIP12	ENSCANP00000021890	ENSCANP00000002725	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Thyroid hormone receptor interactor 12.	0.954
ATG7	UBE2D1	ENSCANP00000021890	ENSCANP00000010288	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family.	0.547
DDIT4	AREL1	ENSCANP00000019615	ENSCANP00000010475	DNA damage inducible transcript 4.	Apoptosis resistant E3 ubiquitin protein ligase 1.	0.495
ENSCANP00000004314	AREL1	ENSCANP00000004314	ENSCANP00000010475	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Apoptosis resistant E3 ubiquitin protein ligase 1.	0.673
ENSCANP00000004314	ATG7	ENSCANP00000004314	ENSCANP00000021890	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.539
ENSCANP00000004314	ENSCANP00000034772	ENSCANP00000004314	ENSCANP00000034772	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.992