STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEGS1Delta 4-desaturase, sphingolipid 1. (295 aa)    
Predicted Functional Partners:
UGCG
UDP-glucose ceramide glucosyltransferase.
   
 
 0.909
KDSR
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.891
SMPD2
Sphingomyelin phosphodiesterase 2.
     
 0.890
CERS1
TLC domain-containing protein.
   
 0.887
SGMS1
Sphingomyelin synthase 1.
   
 
 0.874
ACER1
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
   
 
 0.871
ASAH1
N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family.
     
 0.869
SPHK2
Sphingosine kinase 2.
    
 0.868
SPHK1
Sphingosine kinase 1.
    
 0.868
CERS6
Ceramide synthase 6.
    
 0.868
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
Server load: low (30%) [HD]