STAM2 protein (Colobus angolensis) - STRING interaction network

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Score

STAM2

Signal transducing adaptor molecule 2. (525 aa)

Predicted Functional Partners:

HGS

0.994

STAMBP

0.981

STAM

0.962

LOC105523183

0.959

ITSN2

0.946

ITSN1

0.946

PTPN23

0.938

STAMBPL1

0.936

JAK3

0.913

TSG101

0.910

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HGS	ITSN1	ENSCANP00000033911	ENSCANP00000022260	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Intersectin 1.	0.946
HGS	ITSN2	ENSCANP00000033911	ENSCANP00000006595	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Intersectin 2.	0.947
HGS	LOC105523183	ENSCANP00000033911	ENSCANP00000011982	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Ubiquitin-like domain-containing protein.	0.990
HGS	PTPN23	ENSCANP00000033911	ENSCANP00000038846	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Protein tyrosine phosphatase non-receptor type 23.	0.792
HGS	STAM	ENSCANP00000033911	ENSCANP00000018036	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Signal transducing adaptor molecule.	0.994
HGS	STAM2	ENSCANP00000033911	ENSCANP00000014640	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Signal transducing adaptor molecule 2.	0.994
HGS	TSG101	ENSCANP00000033911	ENSCANP00000012109	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Tumor susceptibility 101.	0.988
ITSN1	HGS	ENSCANP00000022260	ENSCANP00000033911	Intersectin 1.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	0.946
ITSN1	ITSN2	ENSCANP00000022260	ENSCANP00000006595	Intersectin 1.	Intersectin 2.	0.952
ITSN1	LOC105523183	ENSCANP00000022260	ENSCANP00000011982	Intersectin 1.	Ubiquitin-like domain-containing protein.	0.433
ITSN1	STAM	ENSCANP00000022260	ENSCANP00000018036	Intersectin 1.	Signal transducing adaptor molecule.	0.946
ITSN1	STAM2	ENSCANP00000022260	ENSCANP00000014640	Intersectin 1.	Signal transducing adaptor molecule 2.	0.946
ITSN2	HGS	ENSCANP00000006595	ENSCANP00000033911	Intersectin 2.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	0.947
ITSN2	ITSN1	ENSCANP00000006595	ENSCANP00000022260	Intersectin 2.	Intersectin 1.	0.952
ITSN2	JAK3	ENSCANP00000006595	ENSCANP00000000317	Intersectin 2.	Tyrosine-protein kinase.	0.543
ITSN2	LOC105523183	ENSCANP00000006595	ENSCANP00000011982	Intersectin 2.	Ubiquitin-like domain-containing protein.	0.597
ITSN2	STAM	ENSCANP00000006595	ENSCANP00000018036	Intersectin 2.	Signal transducing adaptor molecule.	0.946
ITSN2	STAM2	ENSCANP00000006595	ENSCANP00000014640	Intersectin 2.	Signal transducing adaptor molecule 2.	0.946
JAK3	ITSN2	ENSCANP00000000317	ENSCANP00000006595	Tyrosine-protein kinase.	Intersectin 2.	0.543
JAK3	STAM	ENSCANP00000000317	ENSCANP00000018036	Tyrosine-protein kinase.	Signal transducing adaptor molecule.	0.896