STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL10Interleukin 10. (178 aa)    
Predicted Functional Partners:
IL10RA
Interleukin 10 receptor subunit alpha.
    
 0.993
TP53BP2
Tumor protein p53 binding protein 2.
    
 0.971
IL10RB
Interleukin 10 receptor subunit beta.
    
 0.965
IFNAR1
Interferon alpha and beta receptor subunit 1.
    
 0.955
IL2RA
Interleukin 2 receptor subunit alpha.
   
 
 0.923
IL23R
Interleukin 23 receptor.
   
 
 0.917
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
   
  
 0.905
IL6R
Interleukin 6 receptor.
     
 0.896
IL4R
Interleukin 4 receptor.
     
 0.892
IL2RB
Interleukin 2 receptor subunit beta.
   
 
 0.890
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
Server load: low (26%) [HD]