STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OEG00069.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)    
Predicted Functional Partners:
guaA
Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.782
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
0.711
OEG00287.1
Pur operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.641
OEF99752.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.593
OEF99021.1
IDEAL domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.544
OEG00066.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the UPF0342 family.
 
     0.532
OEF96936.1
Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
     0.484
OEG00068.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.482
atpB
Hypothetical protein; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.
    
 0.477
OEF99093.1
Calcium-translocating P-type ATPase, SERCA-type; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.476
Your Current Organism:
Vulcanibacillus modesticaldus
NCBI taxonomy Id: 337097
Other names: Bacillus sp. BR, DSM 14931, JCM 12998, V. modesticaldus, strain Br
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