| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OEF99049.1 | OEF99878.1 | BHF71_02365 | BHF71_01515 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Inorganic pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.707 |
| OEF99049.1 | OEF99993.1 | BHF71_02365 | BHF71_06885 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.833 |
| OEF99049.1 | guaA | BHF71_02365 | BHF71_05695 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.852 |
| OEF99049.1 | guaB | BHF71_02365 | BHF71_08060 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.774 |
| OEF99049.1 | ndk | BHF71_02365 | BHF71_03970 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.701 |
| OEF99049.1 | purA | BHF71_02365 | BHF71_07860 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.641 |
| OEF99049.1 | pyrG | BHF71_02365 | BHF71_01405 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.628 |
| OEF99049.1 | rph | BHF71_02365 | BHF71_06880 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.649 |
| OEF99878.1 | OEF99049.1 | BHF71_01515 | BHF71_02365 | Inorganic pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.707 |
| OEF99878.1 | OEF99993.1 | BHF71_01515 | BHF71_06885 | Inorganic pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.707 |
| OEF99878.1 | guaA | BHF71_01515 | BHF71_05695 | Inorganic pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.986 |
| OEF99878.1 | guaB | BHF71_01515 | BHF71_08060 | Inorganic pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.948 |
| OEF99878.1 | murI | BHF71_01515 | BHF71_06855 | Inorganic pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.416 |
| OEF99878.1 | ndk | BHF71_01515 | BHF71_03970 | Inorganic pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.400 |
| OEF99878.1 | purA | BHF71_01515 | BHF71_07860 | Inorganic pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.831 |
| OEF99878.1 | rph | BHF71_01515 | BHF71_06880 | Inorganic pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.714 |
| OEF99993.1 | OEF99049.1 | BHF71_06885 | BHF71_02365 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.833 |
| OEF99993.1 | OEF99878.1 | BHF71_06885 | BHF71_01515 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Inorganic pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.707 |
| OEF99993.1 | glpK | BHF71_06885 | BHF71_01945 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.736 |
| OEF99993.1 | guaA | BHF71_06885 | BHF71_05695 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.879 |
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