| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OEF99996.1 | clpX | BHF71_06905 | BHF71_06900 | ATP-dependent protease LonB; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.605 |
| OEF99996.1 | lon | BHF71_06905 | BHF71_06910 | ATP-dependent protease LonB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Endopeptidase La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.675 |
| OEF99996.1 | tig | BHF71_06905 | BHF71_06895 | ATP-dependent protease LonB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.404 |
| OEG00412.1 | OEG00459.1 | BHF71_00445 | BHF71_00700 | Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Translocation-enhancing protein TepA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S14 family. | 0.637 |
| OEG00412.1 | clpP | BHF71_00445 | BHF71_07630 | Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transposase; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.598 |
| OEG00412.1 | clpX | BHF71_00445 | BHF71_06900 | Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.744 |
| OEG00412.1 | guaB | BHF71_00445 | BHF71_08060 | Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.417 |
| OEG00459.1 | OEG00412.1 | BHF71_00700 | BHF71_00445 | Translocation-enhancing protein TepA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S14 family. | Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.637 |
| OEG00459.1 | clpX | BHF71_00700 | BHF71_06900 | Translocation-enhancing protein TepA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S14 family. | ATP-dependent protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.974 |
| OEG00459.1 | guaB | BHF71_00700 | BHF71_08060 | Translocation-enhancing protein TepA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S14 family. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.560 |
| OEG00459.1 | lon | BHF71_00700 | BHF71_06910 | Translocation-enhancing protein TepA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S14 family. | Endopeptidase La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.526 |
| atpD | clpX | BHF71_01240 | BHF71_06900 | F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. | ATP-dependent protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.743 |
| atpD | ftsH | BHF71_01240 | BHF71_05270 | F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.446 |
| atpD | guaB | BHF71_01240 | BHF71_08060 | F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.808 |
| atpD | tig | BHF71_01240 | BHF71_06895 | F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.598 |
| clpP | OEG00412.1 | BHF71_07630 | BHF71_00445 | Transposase; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.598 |
| clpP | clpX | BHF71_07630 | BHF71_06900 | Transposase; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.995 |
| clpP | ftsH | BHF71_07630 | BHF71_05270 | Transposase; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.426 |
| clpP | guaB | BHF71_07630 | BHF71_08060 | Transposase; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.560 |
| clpP | lon | BHF71_07630 | BHF71_06910 | Transposase; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Endopeptidase La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.628 |
STRING v12.5 is now available!
