node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KTR9_0639 | KTR9_1831 | KTR9_0639 | KTR9_1831 | Putative 2-oxoisovalerate dehydrogenase, dihydrolipoamide dehydrogenase component. | 2-oxoglutarate dehydrogenase, E1 component. | 0.999 |
KTR9_0639 | KTR9_2591 | KTR9_0639 | KTR9_2591 | Putative 2-oxoisovalerate dehydrogenase, dihydrolipoamide dehydrogenase component. | Glutamate dehydrogenase / leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.881 |
KTR9_0639 | KTR9_3065 | KTR9_0639 | KTR9_3065 | Putative 2-oxoisovalerate dehydrogenase, dihydrolipoamide dehydrogenase component. | Pyruvate / 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component,-related enzyme. | 0.999 |
KTR9_0639 | KTR9_3112 | KTR9_0639 | KTR9_3112 | Putative 2-oxoisovalerate dehydrogenase, dihydrolipoamide dehydrogenase component. | Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.988 |
KTR9_0639 | KTR9_4132 | KTR9_0639 | KTR9_4132 | Putative 2-oxoisovalerate dehydrogenase, dihydrolipoamide dehydrogenase component. | Acyl-CoA dehydrogenase. | 0.912 |
KTR9_0639 | gcvH | KTR9_0639 | KTR9_2650 | Putative 2-oxoisovalerate dehydrogenase, dihydrolipoamide dehydrogenase component. | Glycine cleavage system H protein (lipoate- binding); The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.987 |
KTR9_0639 | gcvP | KTR9_0639 | KTR9_2645 | Putative 2-oxoisovalerate dehydrogenase, dihydrolipoamide dehydrogenase component. | Glycine cleavage system, glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.951 |
KTR9_0639 | gcvT | KTR9_0639 | KTR9_3063 | Putative 2-oxoisovalerate dehydrogenase, dihydrolipoamide dehydrogenase component. | Glycine cleavage system T protein (aminomethyltransferase); The glycine cleavage system catalyzes the degradation of glycine. | 0.975 |
KTR9_0639 | glyA | KTR9_0639 | KTR9_1624 | Putative 2-oxoisovalerate dehydrogenase, dihydrolipoamide dehydrogenase component. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.920 |
KTR9_0639 | glyA-2 | KTR9_0639 | KTR9_1858 | Putative 2-oxoisovalerate dehydrogenase, dihydrolipoamide dehydrogenase component. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.920 |
KTR9_1831 | KTR9_0639 | KTR9_1831 | KTR9_0639 | 2-oxoglutarate dehydrogenase, E1 component. | Putative 2-oxoisovalerate dehydrogenase, dihydrolipoamide dehydrogenase component. | 0.999 |
KTR9_1831 | KTR9_2591 | KTR9_1831 | KTR9_2591 | 2-oxoglutarate dehydrogenase, E1 component. | Glutamate dehydrogenase / leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.780 |
KTR9_1831 | KTR9_3065 | KTR9_1831 | KTR9_3065 | 2-oxoglutarate dehydrogenase, E1 component. | Pyruvate / 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component,-related enzyme. | 0.990 |
KTR9_1831 | KTR9_3112 | KTR9_1831 | KTR9_3112 | 2-oxoglutarate dehydrogenase, E1 component. | Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.915 |
KTR9_1831 | gcvH | KTR9_1831 | KTR9_2650 | 2-oxoglutarate dehydrogenase, E1 component. | Glycine cleavage system H protein (lipoate- binding); The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.970 |
KTR9_1831 | gcvP | KTR9_1831 | KTR9_2645 | 2-oxoglutarate dehydrogenase, E1 component. | Glycine cleavage system, glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.962 |
KTR9_1831 | gcvT | KTR9_1831 | KTR9_3063 | 2-oxoglutarate dehydrogenase, E1 component. | Glycine cleavage system T protein (aminomethyltransferase); The glycine cleavage system catalyzes the degradation of glycine. | 0.870 |
KTR9_1831 | glyA | KTR9_1831 | KTR9_1624 | 2-oxoglutarate dehydrogenase, E1 component. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.699 |
KTR9_1831 | glyA-2 | KTR9_1831 | KTR9_1858 | 2-oxoglutarate dehydrogenase, E1 component. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.699 |
KTR9_2591 | KTR9_0639 | KTR9_2591 | KTR9_0639 | Glutamate dehydrogenase / leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Putative 2-oxoisovalerate dehydrogenase, dihydrolipoamide dehydrogenase component. | 0.881 |