STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKAN_00861000Putative DNA primase large subunit. (432 aa)    
Predicted Functional Partners:
CKAN_02587700
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
  
 0.999
CKAN_01436800
DNA polymerase.
   
 0.999
CKAN_02631500
DNA polymerase alpha subunit B.
   
 0.999
CKAN_02657900
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
   
 0.997
CKAN_00500300
DNA-directed DNA polymerase.
   
 0.993
CKAN_02200600
DNA polymerase.
   
 0.993
CKAN_01525500
DNA helicase; Belongs to the MCM family.
   
 
 0.987
CKAN_02529700
DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.
   
 0.986
CKAN_02288300
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
   
 0.985
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 0.985
Your Current Organism:
Cinnamomum micranthum
NCBI taxonomy Id: 337451
Other names: C. micranthum f. kanehirae, Cinnamomum kanehirae, Cinnamomum kanehirae Hayata, Cinnamomum kanehirai, Cinnamomum micranthum f. kanehirae, Cinnamomum micranthum f. kanehirae (Hayata) S.S.Ying, Cinnamomum micranthum f. kanehirai
Server load: low (28%) [HD]