node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CKAN_00129700 | CKAN_00303400 | A0A443N3E2 | A0A3S3MJ34 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | ERCC4 domain-containing protein. | 0.963 |
CKAN_00129700 | CKAN_00596000 | A0A443N3E2 | A0A3S3MPR0 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Tudor domain-containing protein 3. | 0.995 |
CKAN_00129700 | CKAN_00806100 | A0A443N3E2 | A0A3S5WGH3 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.934 |
CKAN_00129700 | CKAN_01443100 | A0A443N3E2 | A0A443P472 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Exonuclease 1 isoform X1. | 0.779 |
CKAN_00129700 | CKAN_01517400 | A0A443N3E2 | A0A443P669 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Exonuclease 1 isoform X1. | 0.779 |
CKAN_00129700 | CKAN_01579200 | A0A443N3E2 | A0A3S3PAV2 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | ATP-dependent DNA helicase mph1 isoform X1. | 0.982 |
CKAN_00129700 | CKAN_01605800 | A0A443N3E2 | A0A3S3NV14 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | DNA repair protein RAD50. | 0.893 |
CKAN_00129700 | CKAN_01880500 | A0A443N3E2 | A0A3S3NZC8 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | DNA replication ATP-dependent helicase/nuclease DNA2. | 0.832 |
CKAN_00129700 | CKAN_02054700 | A0A443N3E2 | A0A443PKT9 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | DNA repair protein XRCC3. | 0.776 |
CKAN_00129700 | CKAN_02092300 | A0A443N3E2 | A0A3S3MXD2 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Serine/threonine-protein kinase ATR isoform X1. | 0.797 |
CKAN_00303400 | CKAN_00129700 | A0A3S3MJ34 | A0A443N3E2 | ERCC4 domain-containing protein. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.963 |
CKAN_00303400 | CKAN_00596000 | A0A3S3MJ34 | A0A3S3MPR0 | ERCC4 domain-containing protein. | Tudor domain-containing protein 3. | 0.989 |
CKAN_00303400 | CKAN_00806100 | A0A3S3MJ34 | A0A3S5WGH3 | ERCC4 domain-containing protein. | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.925 |
CKAN_00303400 | CKAN_01443100 | A0A3S3MJ34 | A0A443P472 | ERCC4 domain-containing protein. | Exonuclease 1 isoform X1. | 0.953 |
CKAN_00303400 | CKAN_01517400 | A0A3S3MJ34 | A0A443P669 | ERCC4 domain-containing protein. | Exonuclease 1 isoform X1. | 0.953 |
CKAN_00303400 | CKAN_01579200 | A0A3S3MJ34 | A0A3S3PAV2 | ERCC4 domain-containing protein. | ATP-dependent DNA helicase mph1 isoform X1. | 0.986 |
CKAN_00303400 | CKAN_01605800 | A0A3S3MJ34 | A0A3S3NV14 | ERCC4 domain-containing protein. | DNA repair protein RAD50. | 0.844 |
CKAN_00303400 | CKAN_01880500 | A0A3S3MJ34 | A0A3S3NZC8 | ERCC4 domain-containing protein. | DNA replication ATP-dependent helicase/nuclease DNA2. | 0.890 |
CKAN_00303400 | CKAN_02054700 | A0A3S3MJ34 | A0A443PKT9 | ERCC4 domain-containing protein. | DNA repair protein XRCC3. | 0.911 |
CKAN_00303400 | CKAN_02092300 | A0A3S3MJ34 | A0A3S3MXD2 | ERCC4 domain-containing protein. | Serine/threonine-protein kinase ATR isoform X1. | 0.937 |