CKAN_01484800 protein (Cinnamomum micranthum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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Textmining

[Homology]

Score

CKAN_01484800

Endoplasmin. (912 aa)

Predicted Functional Partners:

CKAN_00146800

0.991

CKAN_01089100

0.991

CKAN_00883900

0.991

CKAN_01576100

0.980

CKAN_01047900

0.971

CKAN_02125900

0.961

CKAN_00333500

0.961

CKAN_00036100

0.961

CKAN_02454400

0.932

CKAN_02617400

0.932

Your Current Organism:

Cinnamomum micranthum

NCBI taxonomy Id: 337451
Other names: C. micranthum f. kanehirae, Cinnamomum kanehirae, Cinnamomum kanehirae Hayata, Cinnamomum kanehirai, Cinnamomum micranthum f. kanehirae, Cinnamomum micranthum f. kanehirae (Hayata) S.S.Ying, Cinnamomum micranthum f. kanehirai

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CKAN_00036100	CKAN_00333500	A0A443N0U5	A0A3S3NTJ6	Luminal-binding protein 4; Belongs to the heat shock protein 70 family.	Luminal-binding protein.	0.784
CKAN_00036100	CKAN_01047900	A0A443N0U5	A0A443NTE8	Luminal-binding protein 4; Belongs to the heat shock protein 70 family.	Heat shock protein 17.	0.998
CKAN_00036100	CKAN_01484800	A0A443N0U5	A0A443P5D8	Luminal-binding protein 4; Belongs to the heat shock protein 70 family.	Endoplasmin.	0.961
CKAN_00036100	CKAN_02454400	A0A443N0U5	A0A3S3N9W1	Luminal-binding protein 4; Belongs to the heat shock protein 70 family.	Calreticulin.	0.889
CKAN_00036100	CKAN_02617400	A0A443N0U5	A0A3S3NK73	Luminal-binding protein 4; Belongs to the heat shock protein 70 family.	Calreticulin.	0.894
CKAN_00146800	CKAN_00883900	A0A3S3MQW0	A0A443NNV2	Protein SGT1 A.	Suppressor of G2 allele of SKP1.	0.855
CKAN_00146800	CKAN_01089100	A0A3S3MQW0	A0A3S4NVI9	Protein SGT1 A.	CS domain-containing protein.	0.854
CKAN_00146800	CKAN_01484800	A0A3S3MQW0	A0A443P5D8	Protein SGT1 A.	Endoplasmin.	0.991
CKAN_00146800	CKAN_01576100	A0A3S3MQW0	A0A443P7V8	Protein SGT1 A.	Cysteine and histidine-rich domain-containing protein RAR1-like protein isoform X1.	0.996
CKAN_00333500	CKAN_00036100	A0A3S3NTJ6	A0A443N0U5	Luminal-binding protein.	Luminal-binding protein 4; Belongs to the heat shock protein 70 family.	0.784
CKAN_00333500	CKAN_01047900	A0A3S3NTJ6	A0A443NTE8	Luminal-binding protein.	Heat shock protein 17.	0.998
CKAN_00333500	CKAN_01484800	A0A3S3NTJ6	A0A443P5D8	Luminal-binding protein.	Endoplasmin.	0.961
CKAN_00333500	CKAN_02125900	A0A3S3NTJ6	A0A3S3MXX6	Luminal-binding protein.	Luminal-binding protein 5; Belongs to the heat shock protein 70 family.	0.784
CKAN_00333500	CKAN_02454400	A0A3S3NTJ6	A0A3S3N9W1	Luminal-binding protein.	Calreticulin.	0.889
CKAN_00333500	CKAN_02617400	A0A3S3NTJ6	A0A3S3NK73	Luminal-binding protein.	Calreticulin.	0.890
CKAN_00883900	CKAN_00146800	A0A443NNV2	A0A3S3MQW0	Suppressor of G2 allele of SKP1.	Protein SGT1 A.	0.855
CKAN_00883900	CKAN_01089100	A0A443NNV2	A0A3S4NVI9	Suppressor of G2 allele of SKP1.	CS domain-containing protein.	0.855
CKAN_00883900	CKAN_01484800	A0A443NNV2	A0A443P5D8	Suppressor of G2 allele of SKP1.	Endoplasmin.	0.991
CKAN_00883900	CKAN_01576100	A0A443NNV2	A0A443P7V8	Suppressor of G2 allele of SKP1.	Cysteine and histidine-rich domain-containing protein RAR1-like protein isoform X1.	0.996
CKAN_01047900	CKAN_00036100	A0A443NTE8	A0A443N0U5	Heat shock protein 17.	Luminal-binding protein 4; Belongs to the heat shock protein 70 family.	0.998

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

35

average node degree:

6.36

avg. local clustering coefficient:

0.716

expected number of edges:

10

PPI enrichment p-value:

7.08e-10

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006631

Fatty acid metabolic process

3 of 14

1.73

1.19

0.0035

GO:0006412

Translation

6 of 91

1.21

1.08

0.00066

GO:0019538

Protein metabolic process

7 of 249

0.84

0.67

0.0019

GO:0044249

Cellular biosynthetic process

8 of 458

0.64

0.46

0.0060

GO:1901576

Organic substance biosynthetic process

8 of 477

0.62

0.44

0.0075

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

6 of 49

1.48

1.8

1.11e-05

GO:0019843

rRNA binding

5 of 39

1.5

1.63

6.39e-05

GO:0000036

Acyl carrier activity

2 of 2

2.39

1.11

0.0092

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

6 of 52

1.46

1.86

4.25e-06

GO:0015934

Large ribosomal subunit

2 of 6

1.92

1.04

0.0098

GO:0005622

Intracellular anatomical structure

9 of 907

0.39

0.28

0.0269

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:186

rRNA-binding

6 of 15

2.0

3.4

2.30e-08

CL:187

Mixed, incl. Large ribosomal subunit, and tRNA-binding

5 of 9

2.14

3.3

1.30e-07

CL:153

Peptide metabolic process, and Proton channel activity

7 of 149

1.07

1.12

2.31e-05

CL:1783

Mixed, incl. Steroid biosynthesis, and ANL, N-terminal domain

2 of 7

1.85

0.97

0.0130

CL:1684

Mixed, incl. Oxidative phosphorylation, and Terpenoid metabolic process

4 of 62

1.2

0.95

0.0025

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

6 of 49

1.48

1.95

2.36e-06

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

5 of 34

1.56

1.74

4.64e-05

GOCC:0015934

Large ribosomal subunit

3 of 6

2.09

1.71

0.00047

GOCC:0022625

Cytosolic large ribosomal subunit

2 of 3

2.22

1.31

0.0035

GOCC:0043232

Intracellular non-membrane-bounded organelle

6 of 131

1.06

0.95

0.00047

GOCC:0043229

Intracellular organelle

7 of 274

0.8

0.66

0.0010

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

6 of 51

1.47

1.85

5.24e-06

KW-0687

Ribonucleoprotein

6 of 51

1.47

1.85

5.24e-06

KW-0699

rRNA-binding

5 of 38

1.51

1.77

2.14e-05

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