CKAN_02155600 protein (Cinnamomum micranthum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CKAN_02155600

Protein FREE1-like protein. (568 aa)

Predicted Functional Partners:

CKAN_00393300

0.796

CKAN_02018100

0.796

CKAN_00767900

0.784

CKAN_02503500

0.784

CKAN_01378600

0.746

CKAN_00118400

0.727

CKAN_02498800

0.727

CKAN_00057300

0.723

CKAN_01182800

0.723

CKAN_00066700

0.723

Your Current Organism:

Cinnamomum micranthum

NCBI taxonomy Id: 337451
Other names: C. micranthum f. kanehirae, Cinnamomum kanehirae, Cinnamomum kanehirae Hayata, Cinnamomum kanehirai, Cinnamomum micranthum f. kanehirae, Cinnamomum micranthum f. kanehirae (Hayata) S.S.Ying, Cinnamomum micranthum f. kanehirai

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CKAN_00057300	CKAN_02155600	A0A3S3MEK8	A0A443PNH8	Ras-related protein Rab7.	Protein FREE1-like protein.	0.723
CKAN_00066700	CKAN_00118400	A0A443N1R8	A0A3S3M475	Ras-related protein Rab7.	Ras-related protein Rab7.	0.812
CKAN_00066700	CKAN_02155600	A0A443N1R8	A0A443PNH8	Ras-related protein Rab7.	Protein FREE1-like protein.	0.723
CKAN_00066700	CKAN_02498800	A0A443N1R8	A0A3S4PW96	Ras-related protein Rab7.	Ras-related protein Rab7.	0.813
CKAN_00118400	CKAN_00066700	A0A3S3M475	A0A443N1R8	Ras-related protein Rab7.	Ras-related protein Rab7.	0.812
CKAN_00118400	CKAN_01182800	A0A3S3M475	A0A3S3N0K0	Ras-related protein Rab7.	Ras-related protein Rab7.	0.812
CKAN_00118400	CKAN_02155600	A0A3S3M475	A0A443PNH8	Ras-related protein Rab7.	Protein FREE1-like protein.	0.727
CKAN_00393300	CKAN_00767900	A0A3S3NA38	A0A3S3MT58	Calcium uptake protein 1, mitochondrial-like protein isoform X1.	Calcium uniporter protein 6, mitochondrial-like protein.	0.961
CKAN_00393300	CKAN_02155600	A0A3S3NA38	A0A443PNH8	Calcium uptake protein 1, mitochondrial-like protein isoform X1.	Protein FREE1-like protein.	0.796
CKAN_00393300	CKAN_02503500	A0A3S3NA38	A0A443PY44	Calcium uptake protein 1, mitochondrial-like protein isoform X1.	Calcium uniporter protein 2, mitochondrial-like protein.	0.961
CKAN_00767900	CKAN_00393300	A0A3S3MT58	A0A3S3NA38	Calcium uniporter protein 6, mitochondrial-like protein.	Calcium uptake protein 1, mitochondrial-like protein isoform X1.	0.961
CKAN_00767900	CKAN_02018100	A0A3S3MT58	A0A3S3P1E9	Calcium uniporter protein 6, mitochondrial-like protein.	EF-hand domain-containing protein.	0.961
CKAN_00767900	CKAN_02155600	A0A3S3MT58	A0A443PNH8	Calcium uniporter protein 6, mitochondrial-like protein.	Protein FREE1-like protein.	0.784
CKAN_01182800	CKAN_00118400	A0A3S3N0K0	A0A3S3M475	Ras-related protein Rab7.	Ras-related protein Rab7.	0.812
CKAN_01182800	CKAN_02155600	A0A3S3N0K0	A0A443PNH8	Ras-related protein Rab7.	Protein FREE1-like protein.	0.723
CKAN_01182800	CKAN_02498800	A0A3S3N0K0	A0A3S4PW96	Ras-related protein Rab7.	Ras-related protein Rab7.	0.813
CKAN_01378600	CKAN_02155600	A0A3S3NCJ7	A0A443PNH8	Phosphatidylinositol 3-/4-kinase; Belongs to the PI3/PI4-kinase family.	Protein FREE1-like protein.	0.746
CKAN_02018100	CKAN_00767900	A0A3S3P1E9	A0A3S3MT58	EF-hand domain-containing protein.	Calcium uniporter protein 6, mitochondrial-like protein.	0.961
CKAN_02018100	CKAN_02155600	A0A3S3P1E9	A0A443PNH8	EF-hand domain-containing protein.	Protein FREE1-like protein.	0.796
CKAN_02018100	CKAN_02503500	A0A3S3P1E9	A0A443PY44	EF-hand domain-containing protein.	Calcium uniporter protein 2, mitochondrial-like protein.	0.961

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

37

average node degree:

6.73

avg. local clustering coefficient:

0.86

expected number of edges:

11

PPI enrichment p-value:

7.2e-10

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0007018

Microtubule-based movement

7 of 32

2.29

5.16

1.09e-11

GO:0007017

Microtubule-based process

8 of 78

1.96

4.38

1.09e-11

GO:0010970

Transport along microtubule

5 of 15

2.47

4.07

1.16e-08

GO:0051293

Establishment of spindle localization

4 of 11

2.51

3.29

5.33e-07

GO:0000226

Microtubule cytoskeleton organization

6 of 63

1.93

3.26

2.70e-08

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0045505

Dynein intermediate chain binding

3 of 3

2.95

2.46

3.27e-05

GO:0045504

Dynein heavy chain binding

2 of 2

2.95

1.36

0.0035

GO:0005515

Protein binding

8 of 756

0.97

0.92

0.00014

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030286

Dynein complex

6 of 7

2.88

6.6

3.39e-13

GO:0005875

Microtubule associated complex

7 of 23

2.43

6.04

3.39e-13

GO:0005868

Cytoplasmic dynein complex

4 of 4

2.95

4.33

1.03e-08

GO:0005874

Microtubule

5 of 58

1.88

2.74

6.03e-07

GO:0005856

Cytoskeleton

8 of 239

1.47

2.4

6.59e-09

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2858

Cytoplasmic dynein complex

5 of 5

2.95

5.14

2.87e-10

CL:3916

Dynactin complex, and F-actin capping protein complex

4 of 11

2.51

3.38

3.59e-07

CL:3919

Dynactin complex

2 of 5

2.55

1.33

0.0036

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04145

Phagosome

3 of 64

1.62

1.02

0.0073

map05132

Salmonella infection

2 of 21

1.93

0.87

0.0216

map04144

Endocytosis

3 of 172

1.19

0.59

0.0420

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-6811436

COPI-independent Golgi-to-ER retrograde traffic

4 of 13

2.43

3.16

8.44e-07

MAP-6807878

COPI-mediated anterograde transport

5 of 46

1.98

2.81

8.44e-07

MAP-3371497

HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand

4 of 31

2.06

2.56

5.29e-06

MAP-199977

ER to Golgi Anterograde Transport

5 of 81

1.74

2.3

3.29e-06

MAP-948021

Transport to the Golgi and subsequent modification

5 of 86

1.71

2.25

3.76e-06

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0030286

Dynein complex

6 of 8

2.82

6.32

1.02e-12

GOCC:0005875

Microtubule associated complex

7 of 69

1.95

4.09

1.02e-10

GOCC:0015630

Microtubule cytoskeleton

9 of 159

1.7

3.7

1.85e-12

GOCC:0005856

Cytoskeleton

10 of 239

1.57

3.25

1.02e-12

GOCC:0035974

Meiotic spindle pole body

2 of 3

2.77

1.54

0.0016

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0206

Cytoskeleton

2 of 16

2.04

0.74

0.0409

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF12455

Dynein associated protein

2 of 2

2.95

1.19

0.0070

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR022157

Dynein associated protein

2 of 2

2.95

0.95

0.0193

IPR036859

CAP Gly-rich domain superfamily

2 of 5

2.55

0.81

0.0336

IPR000938

CAP Gly-rich domain

2 of 5

2.55

0.81

0.0336

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01052

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including ...

2 of 5

2.55

1.15

0.0078

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (16%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About