CKAN_02365600 protein (Cinnamomum micranthum)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

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[Homology]

Score

CKAN_02365600

Exportin-2-like protein. (240 aa)

Predicted Functional Partners:

CKAN_02365700

0.928

CKAN_00491400

0.924

CKAN_02494000

0.924

CKAN_02390200

0.924

CKAN_02392000

0.924

CKAN_02365800

0.922

CKAN_00592600

0.789

CKAN_01180800

0.789

CKAN_00060500

0.789

CKAN_00275100

0.712

Your Current Organism:

Cinnamomum micranthum

NCBI taxonomy Id: 337451
Other names: C. micranthum f. kanehirae, Cinnamomum kanehirae, Cinnamomum kanehirae Hayata, Cinnamomum kanehirai, Cinnamomum micranthum f. kanehirae, Cinnamomum micranthum f. kanehirae (Hayata) S.S.Ying, Cinnamomum micranthum f. kanehirai

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CKAN_00060500	CKAN_00491400	A0A443N1I2	A0A3S3MHD4	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Importin subunit alpha; Belongs to the importin alpha family.	0.812
CKAN_00060500	CKAN_02365600	A0A443N1I2	A0A443PUC3	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Exportin-2-like protein.	0.789
CKAN_00060500	CKAN_02365700	A0A443N1I2	A0A443PUD4	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Exportin-2.	0.789
CKAN_00060500	CKAN_02365800	A0A443N1I2	A0A443PUD2	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Exportin-2.	0.789
CKAN_00060500	CKAN_02390200	A0A443N1I2	A0A443PUZ5	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Importin subunit alpha; Belongs to the importin alpha family.	0.812
CKAN_00060500	CKAN_02392000	A0A443N1I2	A0A443PV31	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	GATA transcription factor-like protein.	0.812
CKAN_00060500	CKAN_02494000	A0A443N1I2	A0A3S3PQD5	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Importin subunit alpha; Belongs to the importin alpha family.	0.812
CKAN_00275100	CKAN_02365600	A0A3S3MT95	A0A443PUC3	ABC transporter E family member 2.	Exportin-2-like protein.	0.712
CKAN_00275100	CKAN_02365700	A0A3S3MT95	A0A443PUD4	ABC transporter E family member 2.	Exportin-2.	0.712
CKAN_00275100	CKAN_02365800	A0A3S3MT95	A0A443PUD2	ABC transporter E family member 2.	Exportin-2.	0.712
CKAN_00491400	CKAN_00060500	A0A3S3MHD4	A0A443N1I2	Importin subunit alpha; Belongs to the importin alpha family.	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.812
CKAN_00491400	CKAN_00592600	A0A3S3MHD4	A0A3S3Q2I4	Importin subunit alpha; Belongs to the importin alpha family.	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.812
CKAN_00491400	CKAN_01180800	A0A3S3MHD4	A0A3S4NXW3	Importin subunit alpha; Belongs to the importin alpha family.	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.812
CKAN_00491400	CKAN_02365600	A0A3S3MHD4	A0A443PUC3	Importin subunit alpha; Belongs to the importin alpha family.	Exportin-2-like protein.	0.924
CKAN_00491400	CKAN_02365700	A0A3S3MHD4	A0A443PUD4	Importin subunit alpha; Belongs to the importin alpha family.	Exportin-2.	0.939
CKAN_00491400	CKAN_02365800	A0A3S3MHD4	A0A443PUD2	Importin subunit alpha; Belongs to the importin alpha family.	Exportin-2.	0.924
CKAN_00592600	CKAN_00491400	A0A3S3Q2I4	A0A3S3MHD4	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Importin subunit alpha; Belongs to the importin alpha family.	0.812
CKAN_00592600	CKAN_02365600	A0A3S3Q2I4	A0A443PUC3	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Exportin-2-like protein.	0.789
CKAN_00592600	CKAN_02365700	A0A3S3Q2I4	A0A443PUD4	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Exportin-2.	0.789
CKAN_00592600	CKAN_02365800	A0A3S3Q2I4	A0A443PUD2	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Exportin-2.	0.789

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Network Stats

number of nodes:

11

number of edges:

34

average node degree:

6.18

avg. local clustering coefficient:

0.88

expected number of edges:

12

PPI enrichment p-value:

7.14e-08

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006099

Tricarboxylic acid cycle

4 of 30

2.15

2.12

6.84e-05

GO:0006097

Glyoxylate cycle

2 of 2

3.03

1.41

0.0029

GO:0005975

Carbohydrate metabolic process

6 of 447

1.16

0.96

0.0014

GO:0006094

Gluconeogenesis

2 of 12

2.25

0.84

0.0289

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0046912

Acyltransferase activity, acyl groups converted into alkyl on transfer

3 of 13

2.39

1.75

0.00054

GO:0042132

Fructose 1,6-bisphosphate 1-phosphatase activity

2 of 2

3.03

1.34

0.0038

GO:0004108

Citrate (Si)-synthase activity

2 of 2

3.03

1.34

0.0038

GO:0016746

Acyltransferase activity

4 of 188

1.36

0.95

0.0055

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009514

Glyoxysome

2 of 2

3.03

1.33

0.0039

GO:0042597

Periplasmic space

2 of 4

2.73

1.27

0.0049

GO:0005777

Peroxisome

3 of 82

1.59

0.93

0.0118

GO:0005737

Cytoplasm

11 of 4517

0.42

0.32

0.0074

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:9454

Citrate synthase, and Citrate metabolic process

2 of 5

2.63

0.82

0.0323

CL:17099

Mixed, incl. Sequestering of actin monomers, and C4-dicarboxylate transmembrane transporter activity

2 of 5

2.63

0.82

0.0323

CL:11084

Glyoxysome, and Isocitrate lyase

2 of 5

2.63

0.82

0.0323

CL:10111

Glycolytic process, and Insulin effects increased synthesis of Xylulose-5-Phosphate

2 of 18

2.07

0.74

0.0415

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

plj01200

Carbon metabolism

6 of 113

1.75

2.86

5.15e-08

plj00630

Glyoxylate and dicarboxylate metabolism

4 of 36

2.07

2.72

2.29e-06

plj00020

Citrate cycle (TCA cycle)

2 of 28

1.88

1.06

0.0084

plj01210

2-Oxocarboxylic acid metabolism

2 of 32

1.82

1.04

0.0090

plj01110

Biosynthesis of secondary metabolites

5 of 415

1.11

0.96

0.00090

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009514

Glyoxysome

2 of 3

2.85

1.17

0.0078

GOCC:0042597

Periplasmic space

2 of 13

2.22

0.76

0.0406

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00316

Fructose-1-6-bisphosphatase, N-terminal domain

2 of 2

3.03

1.28

0.0050

PF00285

Citrate synthase, C-terminal domain

2 of 3

2.85

1.27

0.0050

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR044015

Fructose-1-6-bisphosphatase class 1, C-terminal

2 of 2

3.03

1.03

0.0141

IPR033391

Fructose-1-6-bisphosphatase class I, N-terminal

2 of 2

3.03

1.03

0.0141

IPR020548

Fructose-1,6-bisphosphatase, active site

2 of 2

3.03

1.03

0.0141

IPR019810

Citrate synthase active site

2 of 2

3.03

1.03

0.0141

IPR000146

Fructose-1,6-bisphosphatase class 1

2 of 2

3.03

1.03

0.0141

(more ...)

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