node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHL59199.1 | SHL59226.1 | SAMN05444398_10414 | SAMN05444398_10415 | Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB. | Glutathione S-transferase. | 0.711 |
SHL59199.1 | SHL71320.1 | SAMN05444398_10414 | SAMN05444398_1058 | Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB. | ATP-binding protein involved in chromosome partitioning; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | 0.499 |
SHL59199.1 | SHL85698.1 | SAMN05444398_10414 | SAMN05444398_106150 | Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB. | Oxygen-independent coproporphyrinogen-3 oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.472 |
SHL59199.1 | SHL99810.1 | SAMN05444398_10414 | SAMN05444398_108110 | Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB. | ATP-binding protein involved in chromosome partitioning; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | 0.491 |
SHL59199.1 | SHM33941.1 | SAMN05444398_10414 | SAMN05444398_11435 | Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB. | 16S rRNA (cytosine967-C5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.581 |
SHL59199.1 | dapF | SAMN05444398_10414 | SAMN05444398_10413 | Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.893 |
SHL59199.1 | ftsY | SAMN05444398_10414 | SAMN05444398_105175 | Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.462 |
SHL59199.1 | pnp | SAMN05444398_10414 | SAMN05444398_110114 | Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.461 |
SHL59199.1 | rlmN | SAMN05444398_10414 | SAMN05444398_10379 | Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB. | 23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.555 |
SHL59199.1 | rph | SAMN05444398_10414 | SAMN05444398_106148 | Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB. | RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.758 |
SHL59226.1 | SHL59199.1 | SAMN05444398_10415 | SAMN05444398_10414 | Glutathione S-transferase. | Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB. | 0.711 |
SHL59226.1 | dapF | SAMN05444398_10415 | SAMN05444398_10413 | Glutathione S-transferase. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.709 |
SHL71320.1 | SHL59199.1 | SAMN05444398_1058 | SAMN05444398_10414 | ATP-binding protein involved in chromosome partitioning; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB. | 0.499 |
SHL71320.1 | SHL85698.1 | SAMN05444398_1058 | SAMN05444398_106150 | ATP-binding protein involved in chromosome partitioning; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | Oxygen-independent coproporphyrinogen-3 oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.417 |
SHL85698.1 | SHL59199.1 | SAMN05444398_106150 | SAMN05444398_10414 | Oxygen-independent coproporphyrinogen-3 oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB. | 0.472 |
SHL85698.1 | SHL71320.1 | SAMN05444398_106150 | SAMN05444398_1058 | Oxygen-independent coproporphyrinogen-3 oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | ATP-binding protein involved in chromosome partitioning; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | 0.417 |
SHL85698.1 | SHL99810.1 | SAMN05444398_106150 | SAMN05444398_108110 | Oxygen-independent coproporphyrinogen-3 oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | ATP-binding protein involved in chromosome partitioning; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | 0.417 |
SHL85698.1 | rlmN | SAMN05444398_106150 | SAMN05444398_10379 | Oxygen-independent coproporphyrinogen-3 oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.700 |
SHL85698.1 | rph | SAMN05444398_106150 | SAMN05444398_106148 | Oxygen-independent coproporphyrinogen-3 oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.878 |
SHL99810.1 | SHL59199.1 | SAMN05444398_108110 | SAMN05444398_10414 | ATP-binding protein involved in chromosome partitioning; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB. | 0.491 |