| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KZE17074.1 | KZE21682.1 | AVW13_14320 | AVW13_09525 | Glycine dehydrogenase (aminomethyl-transferring); Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | Serine hydroxymethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.993 |
| KZE17074.1 | KZE22510.1 | AVW13_14320 | AVW13_07445 | Glycine dehydrogenase (aminomethyl-transferring); Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.754 |
| KZE17074.1 | KZE22512.1 | AVW13_14320 | AVW13_07455 | Glycine dehydrogenase (aminomethyl-transferring); Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | Sarcosine oxidase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.772 |
| KZE17074.1 | KZE24508.1 | AVW13_14320 | AVW13_00275 | Glycine dehydrogenase (aminomethyl-transferring); Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | Sarcosine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.999 |
| KZE17074.1 | KZE24548.1 | AVW13_14320 | AVW13_00530 | Glycine dehydrogenase (aminomethyl-transferring); Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| KZE17074.1 | glyA | AVW13_14320 | AVW13_10495 | Glycine dehydrogenase (aminomethyl-transferring); Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.993 |
| KZE21682.1 | KZE17074.1 | AVW13_09525 | AVW13_14320 | Serine hydroxymethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase (aminomethyl-transferring); Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | 0.993 |
| KZE21682.1 | KZE22510.1 | AVW13_09525 | AVW13_07445 | Serine hydroxymethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.452 |
| KZE21682.1 | KZE22512.1 | AVW13_09525 | AVW13_07455 | Serine hydroxymethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sarcosine oxidase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.666 |
| KZE21682.1 | KZE24508.1 | AVW13_09525 | AVW13_00275 | Serine hydroxymethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sarcosine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.890 |
| KZE21682.1 | KZE24548.1 | AVW13_09525 | AVW13_00530 | Serine hydroxymethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.916 |
| KZE22509.1 | KZE22510.1 | AVW13_07440 | AVW13_07445 | Antibiotic biosynthesis monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.517 |
| KZE22510.1 | KZE17074.1 | AVW13_07445 | AVW13_14320 | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase (aminomethyl-transferring); Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | 0.754 |
| KZE22510.1 | KZE21682.1 | AVW13_07445 | AVW13_09525 | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.452 |
| KZE22510.1 | KZE22509.1 | AVW13_07445 | AVW13_07440 | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Antibiotic biosynthesis monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.517 |
| KZE22510.1 | KZE22511.1 | AVW13_07445 | AVW13_07450 | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. | 0.640 |
| KZE22510.1 | KZE22512.1 | AVW13_07445 | AVW13_07455 | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sarcosine oxidase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.546 |
| KZE22510.1 | KZE24508.1 | AVW13_07445 | AVW13_00275 | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sarcosine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.888 |
| KZE22510.1 | KZE24548.1 | AVW13_07445 | AVW13_00530 | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.727 |
| KZE22510.1 | glyA | AVW13_07445 | AVW13_10495 | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.452 |