Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DnaBReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (874 aa)    
Predicted Functional Partners:
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
 
 0.949
DnaA
Chromosomal replication initiator protein DnaA.
 
 
 0.933
RN09_2876
DNA primase; Overlaps another CDS with the same product name.
  
 
 0.931
Ssb
Single-strand DNA-binding protein.
  
 
 0.923
UvrD2
ATP-dependent DNA helicase UvrD.
 
 
 0.921
rplI
50S ribosomal protein L9; Binds to the 23S rRNA.
  
  
 0.900
RN09_3890
ATP-dependent DNA helicase; Overlaps another CDS with the same product name.
 
 
 0.900
RN09_0070
Hypothetical protein.
     
 0.884
RN09_3889
ATP-dependent DNA helicase; Overlaps another CDS with the same product name.
  
 
 0.884
RN09_3576
Insertion sequence element IS1533 transposase.
  
 
 0.857
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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