Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NrpPeptide synthetase Nrp. (2512 aa)    
Predicted Functional Partners:
RN09_0127
Hypothetical protein.
  
  
 0.984
FadD10
fatty-acid--CoA ligase FadD10.
 
  
0.974
PPE1
PPE family protein PPE1; Belongs to the mycobacterial PPE family.
  
  
 0.970
Pks6
Membrane bound polyketide synthase; Overlaps another CDS with the same product name.
 
 0.966
MbtB
Phenyloxazoline synthase.
 
 
0.966
RN09_3555
Phthiocerol synthesis polyketide synthase type I PpsC.
 
 0.965
RN09_0125
Fatty acyl CoA thioesterase FcoT.
  
  
 0.963
RN09_0123
Oxidoreductase; Overlaps another CDS with the same product name.
 
  
 0.959
RN09_3560
Phthiocerol synthesis polyketide synthase type I PpsD; Overlaps another CDS with the same product name.
 
 
 0.955
RN09_0124
Oxidoreductase; Overlaps another CDS with the same product name.
  
  
 0.953
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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