Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Knowledge-based Evidence
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
RN09_01653-hydroxyl-thioester dehydratase. (151 aa)    
Predicted Functional Partners:
FadE30
acyl-CoA dehydrogenase FadE30.
 
 0.963
RN09_4350
Short-chain type dehydrogenase/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 0.954
FadE33
acyl-CoA dehydrogenase FadE33.
 
 0.954
FadB4
NADPH quinone oxidoreductase FadB.
   0.840
RN09_0186
Quinone oxidoreductase.
   0.775
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
      
 0.719
Fgd2
F420-dependent glucose-6-phosphate dehydrogenase.
   
  
 0.715
FadE32
acyl-CoA dehydrogenase FadE32.
 
 0.711
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
  
 0.701
fgd
F420-dependent glucose-6-phosphate dehydrogenase; Catalyzes the coenzyme F420-dependent oxidation of glucose 6- phosphate (G6P) to 6-phosphogluconolactone. Appears to have a role in resistance to oxidative stress, via its consumption of G6P that serves as a source of reducing power to combat oxidative stress in mycobacteria.
   
  
 0.672
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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