Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SigGECF RNA polymerase sigma factor SigG; Belongs to the sigma-70 factor family. ECF subfamily. (332 aa)    
Predicted Functional Partners:
RN09_0224
Hypothetical protein; Belongs to the pirin family.
       0.778
RN09_0227
Hypothetical protein.
       0.715
RN09_0223
Transmembrane protein.
  
    0.712
SigK
ECF RNA polymerase sigma factor SigK; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.684
RN09_0226
Lysophospholipase.
  
  
 0.596
SigD
ECF RNA polymerase sigma factor SigD; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.588
RN09_0228
Hypothetical protein.
       0.562
RN09_4786
ECF RNA polymerase sigma factor SigM; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.528
RN09_0907
anti-sigma-L factor RslA.
  
 
 0.524
RN09_3916
Anti-sigma factor RshA.
  
 
 0.524
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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