Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MmpL3Transmembrane transport protein MmpL3. (912 aa)    
Predicted Functional Partners:
QcrB
Ubiquinol-cytochrome C reductase cytochrome subunit B.
      
 0.861
RN09_0256
Hypothetical protein.
  
  
 0.826
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
  
 0.809
FadD32
long-chain-fatty-acid--AMP ligase FadD32.
    
 
 0.762
RN09_0259
Hypothetical protein.
       0.658
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
      
 0.655
RN09_0494
Transmembrane transport protein MmpL1; Overlaps another CDS with the same product name.
  
     0.640
RN09_3331
Alanine-rich transferase.
  
     0.635
RN09_2691
Endopeptidase; Overlaps another CDS with the same product name.
  
     0.622
RN09_4782
Hypothetical protein.
  
   
 0.621
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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