Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
RN09_0345S-adenosylmethionine-dependent methyltransferase; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. (302 aa)    
Predicted Functional Partners:
RN09_0346
ESX-3 secretion system protein EccA.
 
    0.897
RN09_0347
ESX-3 secretion system protein EccB3.
 
    0.840
RN09_0349
ESX-3 secretion system protein EccC3; Overlaps another CDS with the same product name.
 
    0.811
RN09_0348
ESX-3 secretion system protein EccC3; Overlaps another CDS with the same product name.
 
    0.807
RN09_3344
Hypothetical protein; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
  
     0.760
RN09_0343
PPE family protein PPE3; Overlaps another CDS with the same product name; Belongs to the mycobacterial PPE family.
  
    0.731
PPE3
PPE family protein PPE3; Overlaps another CDS with the same product name; Belongs to the mycobacterial PPE family.
  
    0.731
RN09_0342
PE-PGRS family protein PE_PGRS3.
       0.513
PPE4
PPE family protein PPE4; Belongs to the mycobacterial PPE family.
  
    0.512
RN09_2213
ESX-5 type VII secretion system protein EccA.
  
    0.479
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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