Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN09_0352PPE family protein PPE4. (32 aa)    
Predicted Functional Partners:
PE5
PE family protein PE5.
   
 
 0.962
RN09_0355
ESX-3 secretion-associated protein EspG3.
  
  
 0.892
RN09_0347
ESX-3 secretion system protein EccB3.
  
  
 0.835
RN09_0359
ESX-3 secretion system protein EccE.
  
  
 0.819
RN09_0348
ESX-3 secretion system protein EccC3; Overlaps another CDS with the same product name.
  
  
 0.817
RN09_0349
ESX-3 secretion system protein EccC3; Overlaps another CDS with the same product name.
  
  
 0.817
RN09_0346
ESX-3 secretion system protein EccA.
  
  
 0.797
MycP3
Membrane-anchored mycosin MycP.
  
    0.781
RN09_0357
Transmembrane protein.
  
  
 0.780
EsxG
ESAT-6 like protein EsxG; Belongs to the WXG100 family.
  
  
 0.741
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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