Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Cyp135A1Cytochrome P450 Cyp135A1. (449 aa)    
Predicted Functional Partners:
Pks9
Polyketide synthase; Overlaps another CDS with the same product name.
  
 
 0.754
RN09_0500
Membrane bound polyketide synthase.
  
 0.726
RN09_2045
Polyketide synthase; Overlaps another CDS with the same product name.
  
 0.726
FdxB
Electron transfer protein FdxB.
 
 0.720
FdxD
Ferredoxin FdxD.
  
  
 0.717
Pks11
Chalcone synthase.
   
 
 0.689
RN09_2047
Polyketide synthase; Overlaps another CDS with the same product name.
 
 0.646
Cyp130
Cytochrome P450 Cyp130.
  
  
 0.628
Pks6
Membrane bound polyketide synthase; Overlaps another CDS with the same product name.
  
 0.627
RN09_3555
Phthiocerol synthesis polyketide synthase type I PpsC.
  
 0.627
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
Server load: low (12%) [HD]