node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RN09_0427 | RN09_0428 | RN09_0427 | RN09_0428 | Membrane protein. | Transcriptional regulator. | 0.880 |
RN09_0427 | RN09_0429 | RN09_0427 | RN09_0429 | Membrane protein. | Hypothetical protein. | 0.820 |
RN09_0427 | dnaK | RN09_0427 | RN09_0430 | Membrane protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.450 |
RN09_0427 | grpE | RN09_0427 | RN09_0431 | Membrane protein. | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.450 |
RN09_0428 | RN09_0427 | RN09_0428 | RN09_0427 | Transcriptional regulator. | Membrane protein. | 0.880 |
RN09_0428 | RN09_0429 | RN09_0428 | RN09_0429 | Transcriptional regulator. | Hypothetical protein. | 0.816 |
RN09_0428 | dnaK | RN09_0428 | RN09_0430 | Transcriptional regulator. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.450 |
RN09_0428 | grpE | RN09_0428 | RN09_0431 | Transcriptional regulator. | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.450 |
RN09_0429 | RN09_0427 | RN09_0429 | RN09_0427 | Hypothetical protein. | Membrane protein. | 0.820 |
RN09_0429 | RN09_0428 | RN09_0429 | RN09_0428 | Hypothetical protein. | Transcriptional regulator. | 0.816 |
RN09_0429 | dnaK | RN09_0429 | RN09_0430 | Hypothetical protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.461 |
RN09_0429 | grpE | RN09_0429 | RN09_0431 | Hypothetical protein. | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.461 |
dnaK | RN09_0427 | RN09_0430 | RN09_0427 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Membrane protein. | 0.450 |
dnaK | RN09_0428 | RN09_0430 | RN09_0428 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Transcriptional regulator. | 0.450 |
dnaK | RN09_0429 | RN09_0430 | RN09_0429 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Hypothetical protein. | 0.461 |
dnaK | grpE | RN09_0430 | RN09_0431 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.999 |
grpE | RN09_0427 | RN09_0431 | RN09_0427 | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | Membrane protein. | 0.450 |
grpE | RN09_0428 | RN09_0431 | RN09_0428 | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | Transcriptional regulator. | 0.450 |
grpE | RN09_0429 | RN09_0431 | RN09_0429 | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | Hypothetical protein. | 0.461 |
grpE | dnaK | RN09_0431 | RN09_0430 | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |