Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
RN09_0465HTH-type transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (321 aa)    
Predicted Functional Partners:
RN09_0459
Hypothetical protein.
 
   
 0.871
RN09_0455
Hypothetical protein.
 
     0.861
RN09_0456
Membrane oxidoreductase.
 
     0.821
RN09_0464
Hypothetical protein.
 
   
 0.816
OxyS
Oxidative stress response regulatory protein OxyS; Belongs to the LysR transcriptional regulatory family.
  
    0.814
RN09_3715
TetR family transcriptional regulator.
  
 
 0.809
RN09_4565
AraC/XylS family transcriptional regulator.
  
  
 0.799
RN09_2121
Hypothetical protein.
   
  
 0.784
RN09_2388
Transcriptional regulator.
   
  
 0.773
SigJ
ECF RNA polymerase sigma factor SigJ; Belongs to the sigma-70 factor family.
   
  
 0.772
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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