Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MmpS2Membrane protein MmpS2. (59 aa)    
Predicted Functional Partners:
MmpL2
Transmembrane transport protein MmpL2.
     
 0.859
RN09_0622
Transmembrane transport protein MmpL2.
       0.801
RN09_0624
Hypothetical protein.
       0.801
RN09_0620
Membrane protein MmpS2.
       0.572
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
       0.546
EsxS
ESAT-6 like protein EsxS; Belongs to the WXG100 family.
      
 0.516
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
       0.513
CcdA
Cytochrome C-type biogenesis protein CcdA.
      
 0.511
ArsC
Arsenic-transport integral membrane protein ArsC.
      
 0.511
ArsA
Arsenic-transport integral membrane protein ArsA.
      
 0.511
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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