Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
RN09_0629Transmembrane protein; Overlaps another CDS with the same product name. (182 aa)    
Predicted Functional Partners:
HemD
uroporphyrin-III C-methyltransferase.
  
    0.942
HemB
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
  
    0.879
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
    0.873
RN09_0630
Transmembrane protein; Overlaps another CDS with the same product name.
       0.773
RN09_0631
Hypothetical protein.
       0.773
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
  
    0.746
LppL
Lipoprotein LppL.
  
     0.745
RN09_0632
Hypothetical protein.
       0.732
RN09_4653
Decaprenyl-phosphate phosphoribosyltransferase; Belongs to the UbiA prenyltransferase family.
   
    0.727
RN09_1116
Toxin.
  
     0.722
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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