RN09_0633 protein (Mycobacterium tuberculosis variant africanum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

RN09_0633

Anti-anti-sigma factor. (158 aa)

Predicted Functional Partners:

RsbW

0.788

RN09_1682

0.729

RN09_1683

0.729

FbiC

0.566

RN09_0320

0.529

BfrA

0.510

PknK

0.510

SigF

0.495

RN09_0816

0.484

Mkl

0.484

Your Current Organism:

Mycobacterium tuberculosis variant africanum

NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BfrA	RN09_0633	RN09_2314	RN09_0633	Bacterioferritin BfrA; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.	Anti-anti-sigma factor.	0.510
BfrA	RN09_1682	RN09_2314	RN09_1682	Bacterioferritin BfrA; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.	Sigma factor regulatory protein; Overlaps another CDS with the same product name.	0.438
BfrA	RN09_1683	RN09_2314	RN09_1683	Bacterioferritin BfrA; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.	Sigma factor regulatory protein; Overlaps another CDS with the same product name.	0.511
BfrA	RsbW	RN09_2314	RN09_3992	Bacterioferritin BfrA; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.	Anti-sigma factor RsbW.	0.475
FbiC	RN09_0633	RN09_1451	RN09_0633	FO synthase.	Anti-anti-sigma factor.	0.566
FbiC	RN09_1682	RN09_1451	RN09_1682	FO synthase.	Sigma factor regulatory protein; Overlaps another CDS with the same product name.	0.765
FbiC	RN09_1683	RN09_1451	RN09_1683	FO synthase.	Sigma factor regulatory protein; Overlaps another CDS with the same product name.	0.765
FbiC	RsbW	RN09_1451	RN09_3992	FO synthase.	Anti-sigma factor RsbW.	0.814
Mkl	RN09_0633	RN09_0817	RN09_0633	Ribonucleotide ABC transporter ATP-binding protein.	Anti-anti-sigma factor.	0.484
Mkl	RN09_0816	RN09_0817	RN09_0816	Ribonucleotide ABC transporter ATP-binding protein.	Ribonucleotide ABC transporter ATP-binding protein.	0.993
PknK	RN09_0633	RN09_3744	RN09_0633	Serine/threonine-protein kinase PknK; Overlaps another CDS with the same product name.	Anti-anti-sigma factor.	0.510
RN09_0320	RN09_0633	RN09_0320	RN09_0633	Hypothetical protein.	Anti-anti-sigma factor.	0.529
RN09_0633	BfrA	RN09_0633	RN09_2314	Anti-anti-sigma factor.	Bacterioferritin BfrA; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.	0.510
RN09_0633	FbiC	RN09_0633	RN09_1451	Anti-anti-sigma factor.	FO synthase.	0.566
RN09_0633	Mkl	RN09_0633	RN09_0817	Anti-anti-sigma factor.	Ribonucleotide ABC transporter ATP-binding protein.	0.484
RN09_0633	PknK	RN09_0633	RN09_3744	Anti-anti-sigma factor.	Serine/threonine-protein kinase PknK; Overlaps another CDS with the same product name.	0.510
RN09_0633	RN09_0320	RN09_0633	RN09_0320	Anti-anti-sigma factor.	Hypothetical protein.	0.529
RN09_0633	RN09_0816	RN09_0633	RN09_0816	Anti-anti-sigma factor.	Ribonucleotide ABC transporter ATP-binding protein.	0.484
RN09_0633	RN09_1682	RN09_0633	RN09_1682	Anti-anti-sigma factor.	Sigma factor regulatory protein; Overlaps another CDS with the same product name.	0.729
RN09_0633	RN09_1683	RN09_0633	RN09_1683	Anti-anti-sigma factor.	Sigma factor regulatory protein; Overlaps another CDS with the same product name.	0.729