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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
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mtnPS-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (264 aa)    
Predicted Functional Partners:
GalE3
UDP-glucose 4-epimerase GalE.
 
   
 0.970
Mtn
Bifunctional 5'-methylthioadenosine nucleosidase.
    
 0.968
SpeE
Spermidine synthase; Overlaps another CDS with the same product name.
     
 0.939
YfiH
Laccase domain-containing protein; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.903
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
 
 0.875
RN09_0662
Dolichyl-phosphate sugar synthase.
 
   
 0.822
RN09_0663
Hypothetical protein.
 
   
 0.785
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
       0.779
RN09_0664
Integral membrane protein.
 
   
 0.643
GuaA
GMP synthase.
  
 
 0.554
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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