Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN09_0695Hypothetical protein. (88 aa)    
Predicted Functional Partners:
DevS
Two component sensor histidine kinase DevS.
  
 
 0.841
DevR
Two component transcriptional regulator DevR.
  
  
 0.803
RN09_2470
Universal stress protein.
  
  
 0.712
NrdZ
Vitamin B12-dependent ribonucleoside-diphosphate reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
    0.698
RN09_2500
Two component sensor histidine kinase DosT.
  
 
 0.602
RN09_2139
Hypothetical protein.
  
   
 0.574
RN09_3217
Universal stress protein; Overlaps another CDS with the same product name.
  
  
 0.547
Cyp135B1
Cytochrome P450 Cyp135B1.
       0.523
RN09_2137
Nitrate reductase-like protein NarX; Overlaps another CDS with the same product name.
   
    0.459
RN09_3809
Universal stress protein.
  
  
 0.452
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.