Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RecDExonuclease V subunit alpha RecD; Overlaps another CDS with the same product name. (500 aa)    
Predicted Functional Partners:
RN09_0778
Exonuclease V subunit alpha RecD; Overlaps another CDS with the same product name.
     0.993
RecB
Exonuclease V subunit beta RecB; Overlaps another CDS with the same product name.
 
 0.982
recC
Exonuclease V subunit gamma RecC; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair [...]
 
 0.970
RN09_0782
Exonuclease V subunit beta RecB; Overlaps another CDS with the same product name; Belongs to the helicase family. UvrD subfamily.
 
 
 0.916
UvrD2
ATP-dependent DNA helicase UvrD.
  
 
 0.909
PolA
DNA polymerase I; Overlaps another CDS with the same product name.
 
 
 0.730
DinX
DNA polymerase IV; Belongs to the DNA polymerase type-Y family.
   
 
 0.686
RN09_0777
Hypothetical protein.
       0.646
DinP
DNA polymerase IV 2.
   
 
 0.640
LigC
DNA ligase C.
  
 
 0.624
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.