Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RN09_0791(3R)-hydroxyacyl-ACP dehydratase subunit HadC; Belongs to the UPF0336 family. (166 aa)    
Predicted Functional Partners:
RN09_0790
(3R)-hydroxyacyl-ACP dehydratase subunit HadB.
 0.999
FabG1
3-oxoacyl-ACP reductase FabG1.
 
 0.944
RN09_0617
Hypothetical protein; Belongs to the UPF0336 family.
 
 
 
0.930
InhA
NADH-dependent enoyl-[ACP] reductase.
  
 
 0.925
RN09_0789
(3R)-hydroxyacyl-ACP dehydratase subunit HadA; Belongs to the UPF0336 family.
 
   
0.909
rpsH
30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
   
    0.763
rpmG
50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
     
 0.746
RN09_2763
3-oxoacyl-ACP synthase 2; Overlaps another CDS with the same product name; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
   
 0.666
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
    0.597
EchA3
enoyl-CoA hydratase EchA3.
  
 0.595
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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