Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN09_0882Hypothetical protein. (299 aa)    
Predicted Functional Partners:
RN09_0880
Arylsulfatase AtsA; Overlaps another CDS with the same product name.
 
   0.952
RN09_0881
Arylsulfatase AtsA; Overlaps another CDS with the same product name.
 
   0.894
AtsB
Arylsulfatase AtsB.
 
   0.841
AtsD
Arylsulfatase AtsD.
 
   0.832
RN09_0363
Sulfatase.
 
   0.820
egtD
Histidine-specific methyltransferase EtgD; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family.
 
  
 0.742
egtA
Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine.
  
  
 0.592
RN09_3760
Hypothetical protein.
  
   
 0.563
RN09_3739
Hydrolase.
 
   0.540
RN09_0883
Transmembrane protein.
 
     0.538
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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