Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
RN09_09163-hydroxyisobutyrate dehydrogenase. (48 aa)    
Predicted Functional Partners:
EchA9
enoyl-CoA hydratase EchA9.
  
 
 0.649
FadE9
acyl-CoA dehydrogenase FadE9.
  
  
 0.618
EchA12
enoyl-CoA hydratase EchA12; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.616
RN09_0592
Short-chain type oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 0.586
MmsA
Methylmalonate-semialdehyde dehydrogenase.
  
  
 0.562
RN09_0914
Hypothetical protein.
       0.530
RN09_0915
Transcriptional regulator.
       0.530
RN09_1578
GMC-type oxidoreductase.
   
 
 0.511
MmsB
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
     
 
0.500
RN09_0949
4-carboxymuconolactone decarboxylase.
  
  
 0.462
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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