Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
MmsAMethylmalonate-semialdehyde dehydrogenase. (510 aa)    
Predicted Functional Partners:
MmsB
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
 
 
 0.996
FadE9
acyl-CoA dehydrogenase FadE9.
 
  0.982
GltA1
Methylcitrate synthase PrpC; Belongs to the citrate synthase family.
  
 0.944
GabT
4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.942
FadA5
acetyl-CoA acetyltransferase FadA; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.939
FadA6
acetyl-CoA acetyltransferase FadA.
   
 0.939
Ltp1
Lipid-transfer protein; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.938
PdhC
Branched-chain keto acid dehydrogenase E2 component.
  
 
 0.935
AccD6
acetyl-/propionyl-CoA carboxylase subunit beta.
   
 
 0.933
AccD5
propionyl-CoA carboxylase subunit beta.
   
 
 0.930
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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