Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Cyp123Cytochrome P450 Cyp123. (402 aa)    
Predicted Functional Partners:
Cyp51
Lanosterol 14-alpha demethylase; Belongs to the cytochrome P450 family.
 
  
 0.995
RN09_0943
Oxidoreductase.
 
  
 0.977
RN09_0940
Hypothetical protein.
 
  
 0.945
AldA
Aldehyde dehydrogenase AldA; Belongs to the aldehyde dehydrogenase family.
  
 
 0.943
RN09_0941
Ferredoxin.
 
  
 0.918
RN09_0945
HTH-type transcriptional regulator.
 
   
 0.908
RN09_3370
Oxidoreductase.
 0.877
RN09_0948
Oxidoreductase.
  
    0.817
RN09_0947
Oxidoreductase.
 
   0.790
RN09_2794
Cytochrome P450 Cyp121.
  
   
 0.779
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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