Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
AldAAldehyde dehydrogenase AldA; Belongs to the aldehyde dehydrogenase family. (489 aa)    
Predicted Functional Partners:
AdhB
Alcohol dehydrogenase B.
  
 0.953
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
    
 0.951
RN09_0948
Oxidoreductase.
 
  
 0.945
Cyp123
Cytochrome P450 Cyp123.
  
 
 0.943
GabT
4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.942
RN09_0943
Oxidoreductase.
  
  
 0.940
RN09_0184
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.926
MmsA
Methylmalonate-semialdehyde dehydrogenase.
  
  
 
0.926
AdhA
Alcohol dehydrogenase A.
  
 0.924
Adh
Alcohol dehydrogenase.
  
 0.923
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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