Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CpsYExopolysaccharide phosphotransferase CpsY. (532 aa)    
Predicted Functional Partners:
cpdA
3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
  
  
 0.757
glgB
1,4-alpha-glucan branching protein; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
   
 0.742
TreZ
Malto-oligosyltrehalose trehalohydrolase.
   
 0.742
UvrD2
ATP-dependent DNA helicase UvrD.
    
 
 0.684
RN09_3109
Hypothetical protein.
   
 0.548
RN09_1870
Hypothetical protein.
 
  
 0.534
RN09_1869
Hypothetical protein.
 
  
 0.525
RN09_1641
Glycogen phosphorylase; Overlaps another CDS with the same product name.
  
 
 0.516
GlgP
Glycogen phosphorylase; Overlaps another CDS with the same product name.
  
 
 0.516
RN09_4442
Integral membrane protein.
 
  
 0.511
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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