Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RN09_1012Deaminase. (210 aa)    
Predicted Functional Partners:
RN09_1013
S-adenosylmethionine-dependent methyltransferase; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
 
     0.768
RN09_1011
HTH-type transcriptional regulator KmtR.
       0.574
hisE
phosphoribosyl-ATP pyrophosphatase.
   
  
 0.566
RN09_2693
Hypothetical protein.
  
 
 0.466
RN09_4184
Hypothetical protein.
  
  
 0.466
GuaA
GMP synthase.
  
  
 0.463
RN09_3982
Bifunctional biotin operon repressor/biotin--[acetyl-CoA-carboxylase] synthetase; Overlaps another CDS with the same product name.
  
    0.452
BirA
Bifunctional biotin operon repressor/biotin--[acetyl-CoA-carboxylase] synthetase; Overlaps another CDS with the same product name.
  
    0.452
fbiB
Coenzyme F420:L-glutamate ligase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0. In the N-terminal section; belongs to the CofE family.
  
  
 0.438
RN09_0671
Hypothetical protein.
   
  
 0.433
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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