Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PPE14PPE family protein PPE14; Belongs to the mycobacterial PPE family. (326 aa)    
Predicted Functional Partners:
PE7
PE family protein PE7.
       0.819
RN09_1123
PPE family protein PPE14.
       0.755
LipC
Esterase LipC.
      
 0.557
FadD29
long-chain-fatty-acid--AMP ligase FadD29.
      
 0.531
RN09_1120
Dioxygenase.
       0.529
RN09_1121
Lipid carrier protein or keto acyl-CoA thiolase; Overlaps another CDS with the same product name.
       0.526
RN09_1122
Lipid carrier protein or keto acyl-CoA thiolase; Overlaps another CDS with the same product name.
       0.526
EsxS
ESAT-6 like protein EsxS; Belongs to the WXG100 family.
      
 0.511
ArsC
Arsenic-transport integral membrane protein ArsC.
      
 0.425
ArsA
Arsenic-transport integral membrane protein ArsA.
      
 0.425
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
Server load: low (10%) [HD]