Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN09_1192PE-PGRS family protein PE_PGRS16. (320 aa)    
Predicted Functional Partners:
RN09_4290
PE-PGRS family protein PE_PGRS57.
  
    0.779
RN09_2563
Hypothetical protein.
 
     0.768
RN09_0439
PPE family protein PPE8; Belongs to the mycobacterial PPE family.
  
     0.757
RN09_4087
PPE family protein PPE55; Overlaps another CDS with the same product name; Belongs to the mycobacterial PPE family.
  
     0.757
PE21
Hypothetical protein.
  
     0.756
RN09_4091
PPE family protein PPE56.
  
     0.751
RN09_4083
PPE family protein PPE55; Overlaps another CDS with the same product name.
  
     0.750
PPE6
PPE family protein PPE5.
  
     0.748
RN09_0438
PPE family protein PPE8.
  
     0.748
PPE54
PPE family protein PPE54; Belongs to the mycobacterial PPE family.
  
     0.739
Your Current Organism:
Mycobacterium tuberculosis variant africanum
NCBI taxonomy Id: 33894
Other names: ATCC 25420, CIP 105147, M. tuberculosis variant africanum, Mycobacterium africanum
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